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Join neuroscientist, philosopher, and best-selling author Sam Harris as he explores important and controversial questions about the human mind, society, and current events. The Making Sense podcast was selected by Apple as one of iTunes Best of 2015.

Harris is the author of the best-selling books The End of Faith, Letter to a Christian Nation, The Moral Landscape, Free Will,  Lying, and Waking Up—along with Islam and the Future of Tolerance: A Dialogue (with Maajid Nawaz). The End of Faith won the 2005 PEN Award for Nonfiction. His writing and public lectures cover a wide range of topics—neuroscience, moral philosophy, religion, meditation practice, human violence, rationality—but generally focus on how a growing understanding of ourselves and the world is changing our sense of how we should live.

Harris’s work has been published in more than 20 languages and has been discussed in The New York Times, Time, Scientific American, Nature, Rolling Stone, and many other journals. He has written for The New York Times, The Los Angeles Times, The Economist, The Times (London), The Boston Globe, The Atlantic, The Annals of Neurology, and elsewhere.

Sam Harris received a degree in philosophy from Stanford University and a Ph.D. in neuroscience from UCLA.

Sam Harris's blog and podcast, and much more, can be found at samharris.org.

 

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  2. #436 — A Crisis of Trust

#436 — A Crisis of Trust

Oct 3, 2025

Sam Harris speaks with Michael Osterholm about his new book, The Big One: How We Must Prepare for Future Deadly Pandemics. They discuss the lessons learned from the COVID-19 pandemic, the major mistakes made in the public health response—including lockdowns, school closures, and border policies—the science of airborne versus droplet transmission, the promise and controversy of mRNA vaccines, the reality of vaccine adverse events, the politicization of vaccine hesitancy, and the erosion of scientific institutions like the CDC and HHS under the Trump administration. Looking forward, they explore the characteristics of a future, more deadly pandemic—what Osterholm calls “The Big One”—and what we should be doing to prepare for it.

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