Making Sense with Sam Harris

Join neuroscientist, philosopher, and best-selling author Sam Harris as he explores important and controversial questions about the human mind, society, and current events. The Making Sense podcast was selected by Apple as one of iTunes Best of 2015.

Harris is the author of the best-selling books The End of Faith, Letter to a Christian Nation, The Moral Landscape, Free Will, Lying, and Waking Up—along with Islam and the Future of Tolerance: A Dialogue (with Maajid Nawaz). The End of Faith won the 2005 PEN Award for Nonfiction. His writing and public lectures cover a wide range of topics—neuroscience, moral philosophy, religion, meditation practice, human violence, rationality—but generally focus on how a growing understanding of ourselves and the world is changing our sense of how we should live.

Harris’s work has been published in more than 20 languages and has been discussed in The New York Times, Time, Scientific American, Nature, Rolling Stone, and many other journals. He has written for The New York Times, The Los Angeles Times, The Economist, The Times (London), The Boston Globe, The Atlantic, The Annals of Neurology, and elsewhere.

Sam Harris received a degree in philosophy from Stanford University and a Ph.D. in neuroscience from UCLA.

Sam Harris's blog and podcast, and much more, can be found at samharris.org.

#488 — Ego, Ecstasy, and Equanimity

Aug 4, 2026

Sam Harris speaks with Neal Brennan about the experiences that shaped his life and work. They discuss Sam's mother's television career, growing up with an absent father, his struggles with perfectionism, his first experience with MDMA, dropping out of Stanford, meditation retreats, spiritual charisma and claims...

#487 — Is AI Already Conscious?

Jul 31, 2026

Sam Harris speaks with Cameron Berg about whether AI systems are or could become conscious. They discuss self-reports in LLMs, what models say when deception is switched off, the "bliss attractor" state, consciousness and sentience, the hard problem of consciousness, parallels between neural networks and...

#486 — Luck All the Way Down

Jul 22, 2026

Sam Harris speaks with Kathryn Paige Harden about behavioral genetics, moral luck, and the problem of blame. They discuss Harden's book Original Sin, the controversy over Charles Murray and Ezra Klein, why behavioral genetics remains taboo, the meaning of heritability, nature and nurture as feedback loops, why...

#485 — The New Science of Cancer

Jul 14, 2026

Sam Harris speaks with Siddhartha Mukherjee about the science of cancer. They discuss the updated edition of The Emperor of All Maladies, whether cancer is one disease or many, why prevention is so hard, inflammation and air pollution as carcinogens, the myth that cell phones cause cancer, liquid biopsies and Bayesian...

#484 — Artificial Intimacy

Jul 8, 2026

Sam Harris speaks with Paul Bloom about our relationships with AI and the future of human connection. They discuss the surprising pace of AI progress, AI companions as a remedy for loneliness, the importance of mattering to other people, digitally resurrecting the dead, whether AI can be conscious, the moral failings of...